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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBL2
All Species:
19.09
Human Site:
Y1057
Identified Species:
35
UniProt:
Q08999
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08999
NP_005602.3
1139
128367
Y1057
L
S
Q
N
H
P
V
Y
I
S
P
H
K
N
E
Chimpanzee
Pan troglodytes
XP_523371
1139
128318
Y1057
L
S
Q
N
H
P
V
Y
I
S
P
H
K
N
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535303
1139
128252
V1056
Q
L
S
Q
N
H
P
V
Y
I
S
P
H
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64700
1135
127455
Y1053
L
S
Q
S
H
P
I
Y
I
S
P
H
N
N
E
Rat
Rattus norvegicus
O55081
1135
127799
Y1053
L
S
Q
S
H
P
I
Y
I
S
P
H
K
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520195
1071
120785
V988
Q
L
S
Q
N
H
S
V
Y
I
S
P
H
K
N
Chicken
Gallus gallus
Q90600
921
104417
K840
G
T
S
E
K
F
Q
K
I
N
Q
M
V
C
N
Frog
Xenopus laevis
NP_001084880
998
113114
Y917
V
S
Q
Q
H
S
I
Y
V
S
P
H
K
N
S
Zebra Danio
Brachydanio rerio
XP_002667000
970
107485
S889
H
N
H
S
I
Y
I
S
P
H
K
T
G
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24472
845
96808
M764
I
Q
Q
S
P
N
Q
M
V
Y
S
F
C
R
S
Honey Bee
Apis mellifera
XP_395096
1006
113492
K925
M
T
R
T
L
D
P
K
A
I
S
A
S
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
S954
S
K
M
D
A
L
I
S
N
S
S
K
S
Y
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKZ3
1013
112157
C932
S
T
K
S
Y
Y
A
C
V
G
E
S
T
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.1
N.A.
90.9
90
N.A.
79.8
21.8
43.2
53
N.A.
23.5
40.2
N.A.
N.A.
Protein Similarity:
100
99.9
N.A.
98.7
N.A.
94.9
94.8
N.A.
87.1
38.3
61.2
65.5
N.A.
40.6
57.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
80
86.6
N.A.
0
6.6
60
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
6.6
N.A.
93.3
100
N.A.
6.6
20
80
26.6
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
39.6
N.A.
N.A.
39.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
8
0
0
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
31
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% G
% His:
8
0
8
0
39
16
0
0
0
8
0
39
16
8
0
% H
% Ile:
8
0
0
0
8
0
39
0
39
24
0
0
0
0
0
% I
% Lys:
0
8
8
0
8
0
0
16
0
0
8
8
31
16
0
% K
% Leu:
31
16
0
0
8
8
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
16
16
8
0
0
8
8
0
0
8
39
24
% N
% Pro:
0
0
0
0
8
31
16
0
8
0
39
16
0
8
8
% P
% Gln:
16
8
47
24
0
0
16
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
16
39
24
39
0
8
8
16
0
47
39
8
16
8
16
% S
% Thr:
0
24
0
8
0
0
0
0
0
0
0
8
8
0
0
% T
% Val:
8
0
0
0
0
0
16
16
24
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
16
0
39
16
8
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _